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            医学检验论文栏目提供最新医学检验论文格式、医学检验硕士论文范文。详情咨询QQ:357500023

            Hcy联合CRP及WBC在冠心病患者中的诊断效果及价值研究

            论文编号:lw201901161430376750 所属栏目:医学检验论文 发布日期:2019年01月16日 论文作者:论文网
            【摘要】目的:观察血清同型半胱氨酸(Hcy)联合C反应蛋白(CRP)及白细胞(WBC)在冠心病患者中的诊断效果及价值。方法:选取2015年1月-2016年6月医院诊治的冠心病患者91例,设为观察组。其中,急性心肌梗死(AMI)25例,不稳定心绞痛(UAP)24例,稳定性心绞痛(SPA)22例。选取同期入院健康体检者33例,设为对照组。采用酶法检测Hcy,采用免疫散射比浊法测定CRP水平,利用XE-5000全自动血液分析仪测定两组WBC水平,分析Hcy联合CRP及WBC在冠心病患者中的诊断效果。结果:观察组患者Hcy联合CRP及WBC水平,显著高于对照组(P<0.05);急性心肌梗死、不稳定心绞痛和稳定性心绞痛Hcy联合CRP及WBC水平,均高于对照组(P<0.05);急性心肌梗死Hcy联合CRP及WBC水平,显著高于不稳定心绞痛和稳定性心绞痛(P<0.05);不稳定心绞痛Hcy联合CRP及WBC水平,显著高于稳定性心绞痛(P<0.05);Hcy指标ROC曲线面积为0.84,CRP指标ROC曲线面积为1,WBC指标ROC曲线面积为0.96。结论:冠心病患者诊断过程中采用Hcy联合CRP及WBC效果理想,能提高临床确诊率,值得推广应用。
            【关键词】血清同型半胱氨酸;C反应蛋白;白细胞;冠心??;诊断效果;确诊率
            [Abstract] Objective: To observe the effect and value of homocysteine uniting with C reactive protein and white blood cell in the in patients with coronary heart disease. Method: Selecting 91 cases of coronary heart disease in the hospital from January 2015 to June 2016, they are set to  be the observation group. Among them, acute myocardial infarction in 25 cases, unstable angina pectoris in 24 cases, and stable angina pectoris in 22 cases. In the same period, 33 patients admitted to hospital were selected as control group. Enzyme assay was used to detect Hcy, and CRP level was measured by immune scatter turbidity method, Using XE-5000 automatic blood analyzer to measure the level of WBC in the two groups, to analyze the diagnostic effect of Hcy combined with CRP and WBC in patients with coronary heart disease. Results: The levels of CRP combined with WBC and Hcy in the observation group were significantly higher than those in the control group (P<0.05); Acute myocardial infarction, unstable angina and stable angina pectoris Hcy combined with CRP and WBC levels were higher than those in the control group (P<0.05); Hcy combined with CRP and WBC levels in patients with acute myocardial infarction was significantly higher than that in patients with unstable angina and stable angina pectoris (P<0.05); Hcy index ROC curve area was 0.84, CRP index ROC curve area was 1 and WBC index ROC curve area was 0.96. Conclusion: the diagnosis effect of coronary heart disease patients using Hcy combined with CRP and WBC is ideal, and it can improve the clinical diagnosis rate, so it is worth popularizing.
            [Key words] serum homocysteine; C reactive protein; white blood cell; coronary heart disease; diagnosis effect; diagnosis rate
            冠心?。╟oronary heart disease,CHD)是由于冠状动脉发展粥样硬化使得管腔狭窄或阻塞等,导致心肌缺血、缺氧等引起的心脏病?;颊叻⒉『蟛±肀浠瓜喽越下?,病情较轻者临床上缺乏特异性症状,病情较重者,将会引起心肌梗塞及猝死等,影响患者健康[1]。目前,临床上对于冠心病主要以冠状动脉造影诊断为主,且该方法一度被认为是冠心病的“金标准”[2]。但是,冠状动脉造影检查属于是一种有创检查,检查费用相对较高,导致患者检查依从性较差。因此,积极寻找一种简便、易行、无创性检查方法对提高临床确诊率具有重要的意义。近年来,Hc)联合CRP及WBC在冠心病患者中得到应用,且效果理想[3]。为了探讨血清同型半胱氨酸(Hcy)联合C反应蛋白(CRP)及白细胞(WBC)在冠心病患者中的诊断效果及价值。选取2015年1月-2016年6月医院诊治的冠心病患者60例,报道如下。
            1.资料与方法
            1.1临床资料
            1.2 方法
            1.3 观察指标
            2.结果
            2.1 检测四个指标在各组中的差异性
            2.2 Hcy联合CRP及WBC水平ROC曲线面积比较
            3.讨论

            【参考文献】

            [1]宋玉莲,白若岑,刘铁峰,等.HCY、CRP、Fib、WBC 水平在冠心病诊断中的临床价值[J].现代生物医学进展,2016,16(13):2493-22496.
            [2]Whelton SP,Roy P,Astor BC,et al. Elevated high-sensitivity c-reactive protein as a risk marker of the attenuated relationship between serum cholesterol and cardiovascular events at older age[J]. American Journal of Epidemiology,2013,178(7): 1076-1084.
            [3]董文斌.盐酸替罗非班应用于冠心病患者临床治疗中的效果探讨[J].世界最新医学信息文摘,2015,15(98):86-87.
            [4]赵永祯,李春盛.生物标志物组合对急诊脓毒症和重度脓毒症患者的诊断价值[J].中华危重病急救医学,2014,26(3):153-158.
            [5]朱少文,张锦兰.不同剂量阿托伐他汀钙治疗脑梗死的效果及对血浆脂蛋白磷脂酶A2的影响[J].中国当代医药,2015,22(12):97-99.
            [6]段明勤,黄改荣,徐先静,等.依折麦布对老年冠心病患者介入治疗术后血脂管理的疗效分析[J].中华老年医学杂志,2013,32(6):592-594.
            [7]张永珍,高炜.稳定性冠心病诊治策略的选择:欧美指南给我们的提示[J].北京大学学报(医学版),2014,46(6):832-835.
            [8]刘文举,唐庆业,李文霞,等.地尔硫卓对择期经皮冠脉介入治疗患者围术期心肌损伤的影响[J].实用医学杂志,2015,31(2):296-298.
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